Dix DB, Khanna G, Renfro LA, Tfirn IC, Smith EA, Artunduaga M, Eklund MJ, Sandberg JK, Parsons LN, Kalapurakal JA, Ehrlich PF, Aldrink JH, Glick RD, Benedetti DJ, Fernandez CV, Dome JS, Mullen EA, Geller JI; COG Renal Tumor Committee. Impact of Pulmonary Tumor Burden in Favorable Histology Wilms Tumor Outcomes: A Report From the Children’s Oncology Group Study AREN0533. J Clin Oncol. 2025 Nov 12:JCO2500532. doi: 10.1200/JCO-25-00532. Epub ahead of print. PMID: 41223336; PMCID: PMC12646512.
Study ID Citation
Abstract
Children with favorable histology Wilms tumor (FHWT) with pulmonary metastases have inferior outcomes compared to those with localized disease. We evaluated the impact of pulmonary tumor burden within subgroups of like-treated children with stage IV FHWT.