Imaging of pediatric renal tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper focused on Wilms tumor and nephrogenic rests

Artunduaga M, Eklund M, van der Beek JN, Hammer M, Littooij AS, Sandberg JK, Schenk JP, Servaes S, Singh S, Smith EA, Srinavasan A, Khanna G. Imaging of pediatric renal tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper focused on Wilms tumor and nephrogenic rests. Pediatr Blood Cancer. 2023 Jun;70 Suppl 4(Suppl 4):e30004. doi: 10.1002/pbc.30004. Epub 2022 Oct 29. PubMed PMID: 36308415; PubMed Central PMCID: PMC10641878.

Malignant renal tumors account for approximately 6% of pediatric malignancies, with Wilms tumor (WT) representing approximately 90% of pediatric renal tumors. This manuscript provides consensus-based imaging guidelines for the initial evaluation of a child with a suspected WT and follow up during and after therapy co-developed by the Children’s Oncology Group (COG) Diagnostic Imaging and Society for Pediatric (SPR) Radiology Oncology Committees. The guidelines for Wilms tumor imaging in the Society of International Pediatric Oncology (SIOP) are briefly discussed to highlight some of the differences in imaging approach.