Millstein J, Rassekh SR, Brown AL, Nie Q, Esbenshade AJ, Knight KR, Scheurer ME, Sung L, Brooks B, Moke DJ, Ross CJD, Wright M, Mena V, Rushing T, Carleton BC, Orgel E. Development and Validation of a Novel Prediction Model for Hearing Loss From Cisplatin Chemotherapy. J Clin Oncol. 2025 Jul;43(19):2173-2183. doi: 10.1200/JCO-24-01861. Epub 2025 May 5. PMID: 40324146; PMCID: PMC12202178.
Study ID Citation
Abstract
Cisplatin treats many common tumors but causes permanent and debilitating hearing loss (HL). The objective of this study was to develop and externally validate a predictive model of HL in cisplatin-treated children and adolescent cancer survivors.