Balyasny S, Lee SM, Desai AV, Volchenboum SL, Naranjo A, Park JR, London WB, Cohn SL, Applebaum MA. Association Between Participation in Clinical Trials and Overall Survival Among Children With Intermediate- or High-risk Neuroblastoma. JAMA Netw Open. 2021 Jul 1;4(7):e2116248. doi: 10.1001/jamanetworkopen.2021.16248. PubMed PMID: 34236408; PubMed Central PMCID: PMC8267607.
Study ID Citation
Abstract
This cohort study of 9087 children with neuroblastoma identified a higher prevalence of favorable prognostic markers among children with intermediate-risk neuroblastoma who were enrolled in clinical trials and more unfavorable features among children with high-risk neuroblastoma compared with risk-matched patients not enrolled in a clinical trial. Overall survival was superior for children with intermediate-risk neuroblastoma who were enrolled in a clinical trial but not children with high-risk neuroblastoma who were enrolled in a clinical trial.